In this Saturday, Oct. 23, 2021, photograph, a sign notifies customers that COVID-19 vaccinations are available at a pharmacy in a grocery store in Monument, Colo. Millions of U.S. workers now have a Jan. 4 deadline to get a COVID vaccine. The federal government on Thursday, Nov. 4, 2021 announced new vaccine requirements for workers at companies with more than 100 employees as well as workers at health care facilities that treat Medicare and Medicaid patients. (AP Photo/David Zalubowski)