In this Nov. 9, 2020, file photo, an ad for COVID-19 testing reflects on glass at a bus stop, as pedestrians walk past Pfizer world headquarters in New York. On Friday, Nov. 20, 2020, Pfizer has asked U.S. regulators to allow emergency use of its COVID-19 vaccine, starting a process that could bring first shots as early as next month. (AP Photo/Bebeto Matthews, File)