NFL opening lines for Weeks 1 through 16
WEEK 1
Baltimore at Denver (-7)
New England (-7) at Buffalo
Tennessee at Pittsburgh (-7)
Atlanta at New Orleans (-1½)
Tampa Bay (-1½) at N.Y. Jets
Kansas City (-3) at Jacksonville
Cincinnati at Chicago (-3)
Miami (-1½) at Cleveland
Seattle (-3½) at Carolina
Minnesota at Detroit (-2½)
Oakland at Indianapolis (-7)
Arizona at St. Louis (-4½)
Green Bay at San Francisco (-4)
N.Y. Giants at Dallas (-2½)
Philadelphia at Washington (-4½)
Houston (-3) at San Diego
WEEK 2
N.Y. Jets at New England (-8)
St. Louis at Atlanta (-7)
Carolina (-1) at Buffalo
Minnesota at Chicago (-2½)
Washington at Green Bay (-4½)
Miami at Indianapolis (Pick)
Dallas (-1½) at Kansas City
Cleveland at Baltimore (-7½)
Tennessee at Houston (-7½)
San Diego at Philadelphia (-2½)
Detroit (-2½) at Arizona
New Orleans (-1½) at Tampa Bay
Jacksonville at Oakland (-3)
Denver (-1) at N.Y. Giants
San Francisco at Seattle (-2½)
Pittsburgh at Cincinnati (-1)
WEEK 3
Kansas City at Philadelphia (-3)
Green Bay at Cincinnati (Pick)
St. Louis at Dallas (-4½)
San Diego (-2½) at Tennessee
Cleveland at Minnesota (-6½)
Tampa Bay at New England (-7½)
Arizona at New Orleans (-7½)
Detroit at Washington (-2½)
N.Y. Giants (-1) at Carolina
Houston at Baltimore (-3½)
Atlanta (-1) at Miami
Buffalo at N.Y. Jets (-3½)
Indianapolis at San Francisco (-7½)
Jacksonville at Seattle (-14)
Chicago at Pittsburgh (-2½)
Oakland at Denver (-13½)
WEEK 4
San Francisco (-4) at St. Louis
Baltimore (-4) at Buffalo
Cincinnati (-3) at Cleveland
Chicago at Detroit (-1)
N.Y. Giants (-1½) at Kansas City
Pittsburgh (-1½) vs. Minnesota (at London)
Arizona at Tampa Bay (-4½)
Indianapolis (-3½) at Jacksonville
Seattle (-1) at Houston
N.Y. Jets (-1) at Tennessee
Philadelphia at Denver (-7½)
Dallas at San Diego (-1)
Washington (-4) at Oakland
New England at Atlanta (Pick)
Miami at New Orleans (-4½)
WEEK 5
Buffalo at Cleveland (-1½)
New Orleans at Chicago (-1)
New England (-1½) at Cincinnati
Jacksonville at St. Louis (-6½)
Baltimore (-1) at Miami
Philadelphia at N.Y. Giants (-4)
Detroit at Green Bay (-4½)
Kansas City at Tennessee (Pick)
Seattle (-4) at Indianapolis
Carolina (-1½) at Arizona
Denver (-2½) at Dallas
San Diego (-2½) at Oakland
Houston at San Francisco (-5½)
N.Y. Jets at Atlanta (-7)
WEEK 6
N.Y. Giants at Chicago (-2½)
Cincinnati (-2½) at Buffalo
Detroit (-1) at Cleveland
Oakland at Kansas City (-4½)
Carolina at Minnesota (-2½)
Philadelphia at Tampa Bay (-1½)
Green Bay at Baltimore (-1)
St. Louis at Houston (-4½)
Pittsburgh (-1½) at N.Y. Jets
Jacksonville at Denver (-14)
Tennessee at Seattle (-11)
New Orleans at New England (-4)
Arizona at San Francisco (-10)
Washington at Dallas (-1½)
Indianapolis at San Diego (-2½)
WEEK 7
Seattle (-6) at Arizona
Tampa Bay at Atlanta (-6)
Cincinnati at Detroit (-1½)
Houston (-2½) at Kansas City
Buffalo at Miami (-4)
New England (-4) at N.Y. Jets
Dallas at Philadelphia (Pick)
Chicago at Washington (-1½)
St. Louis at Carolina (-3½)
San Diego (-3½) at Jacksonville
San Francisco (-7) at Tennessee
Baltimore at Pittsburgh (-1½)
Cleveland at Green Bay (-7½)
Denver (-3½) at Indianapolis
Minnesota at N.Y. Giants (-3)
WEEK 8
Carolina at Tampa Bay (-1½)
Dallas at Detroit (-1)
Cleveland at Kansas City (-2½)
Miami at New England (-7)
Buffalo at New Orleans (-6½)
San Francisco (-10½) vs. Jacksonville (at London)
N.Y. Giants at Philadelphia (Pick)
Pittsburgh (-4½) at Oakland
N.Y. Jets at Cincinnati (-4½)
Washington at Denver (-6)
Atlanta (-4) at Arizona
Green Bay (-1) at Minnesota
Seattle (-4) at St. Louis
WEEK 9
Cincinnati at Miami (-1)
Kansas City at Buffalo (-1½)
San Diego at Washington (-3½)
Atlanta (-1) at Carolina
Minnesota at Dallas (-1½)
Tennessee at St. Louis (-4½)
New Orleans (-1½) at N.Y. Jets
Tampa Bay at Seattle (-7)
Philadelphia (-1½) at Oakland
Pittsburgh at New England (-4)
Baltimore (-3½) at Cleveland
Indianapolis at Houston (-4½)
Chicago at Green Bay (-4)
WEEK 10
Washington at Minnesota (-1½)
Seattle at Atlanta (Pick)
Detroit at Chicago (-3)
Philadelphia at Green Bay (-7)
Jacksonville at Tennessee (-3½)
St. Louis at Indianapolis (-2½)
Oakland at N.Y. Giants (-9)
Buffalo at Pittsburgh (-7)
Cincinnati at Baltimore (-3)
Carolina at San Francisco (-6)
Denver (-3) at San Diego
Houston (-3) at Arizona
Dallas at New Orleans (-4)
Miami at Tampa Bay (-1½)
WEEK 11
Indianapolis (-1) at Tennessee
N.Y. Jets at Buffalo (-1½)
Baltimore at Chicago (Pick)
Cleveland at Cincinnati (-6)
Atlanta (-1) at Tampa Bay
Arizona at Jacksonville (Pick)
Oakland at Houston (-7½)
San Diego at Miami (-3)
Washington at Philadelphia (Pick)
Detroit at Pittsburgh (-3½)
Kansas City at Denver (-7½)
Minnesota at Seattle (-6)
San Francisco at New Orleans (Pick)
Green Bay at N.Y. Giants (Pick)
New England (-3) at Carolina
WEEK 12
New Orleans at Atlanta (-2½)
Pittsburgh (-3) at Cleveland
Tampa Bay at Detroit (-3½)
Minnesota at Green Bay (-4½)
San Diego at Kansas City (-1)
Chicago (-1) at St. Louis
Carolina at Miami (-1½)
N.Y. Jets at Baltimore (-6)
Jacksonville at Houston (-10)
Indianapolis at Arizona (Pick)
Tennessee at Oakland (-1)
Dallas at N.Y. Giants (-2½)
Denver at New England (-1½)
San Francisco (-1½) at Washington
WEEK 13
Green Bay (-1½) at Detroit
Oakland at Dallas (-7)
Pittsburgh at Baltimore (-2½)
Tampa Bay at Carolina (-3)
Jacksonville at Cleveland (-4½)
Tennessee at Indianapolis (-4½)
Denver (-4) at Kansas City
Chicago at Minnesota (-1½)
Miami at N.Y. Jets (-1)
Arizona at Philadelphia (-4)
Atlanta (-3) vs. Buffalo (at Toronto)
St. Louis at San Francisco (-7½)
New England at Houston (Pick)
Cincinnati at San Diego (Pick)
N.Y. Giants at Washington (-1½)
New Orleans at Seattle (-3½)
WEEK 14
Houston (-4½) at Jacksonville
Indianapolis at Cincinnati (-4½)
Buffalo at Tampa Bay (-3)
Kansas City at Washington (-4½)
Minnesota at Baltimore (-3½)
Cleveland at New England (-8½)
Carolina at New Orleans (-3½)
Oakland at N.Y. Jets (-6)
Detroit at Philadelphia (-1)
Miami at Pittsburgh (-3½)
Tennessee at Denver (-10)
N.Y. Giants at San Diego (Pick)
Seattle at San Francisco (-2½)
St. Louis at Arizona (Pick)
Atlanta at Green Bay (-3)
Dallas at Chicago (-3)
WEEK 15
San Diego at Denver (-6½)
Washington at Atlanta (-3)
Chicago (-1½) at Cleveland
Arizona at Tennessee (-1)
Houston at Indianapolis (Pick)
New Orleans (-1½) at St. Louis
New England (-2) at Miami
Philadelphia at Minnesota (-3½)
Seattle (-1) at N.Y. Giants
Buffalo (-1) at Jacksonville
San Francisco (-3) at Tampa Bay
N.Y. Jets at Carolina (-3)
Kansas City at Oakland (Pick)
Green Bay (-1) at Dallas
Cincinnati at Pittsburgh (-2½)
Baltimore at Detroit (Pick)
WEEK 16
Miami at Buffalo (Pick)
Minnesota at Cincinnati (-2½)
Indianapolis at Kansas City (-1)
Tampa Bay at St. Louis (-1)
Cleveland at N.Y. Jets (-3)
Chicago at Philadelphia (Pick)
Dallas at Washington (-2½)
New Orleans at Carolina (Pick)
Tennessee at Jacksonville (Pick)
Denver at Houston (Pick)
Arizona at Seattle (-8½)
N.Y. Giants at Detroit (-1½)
Pittsburgh at Green Bay (-3)
Oakland at San Diego (-4½)
New England at Baltimore (Pick)
Atlanta at San Francisco (-3½)