In this Oct. 20, 2019, file photo, Arizona Cardinals quarterback Kyler Murray is shown during the first half of an NFL football game against the New York Giants, in East Rutherford, N.J. Six months after Kyler Murray was drafted No. 1 by Arizona one spot ahead of him, San Francisco defensive end Nick Bosa gets his opportunity to chase Murray down when the 49ers visit the Cardinals this week. (AP Photo/Adam Hunger)